中心簡介 / 同仁通訊錄

分子科學小組


姓名： 劉振霖( Chen-Lin Liu )
分機： 7207
電子郵件： liu.cl@nsrrc.org.tw
網址： https://sites.google.com/site/johnson0800/home
學歷：
  • 清華大學化學系-中央研究院國際研究生學程物理化學博士(2004年9月~2008年2月)
  • 交通大學應化系物理化學碩士(1999年9月~2001年6月)
  • 交通大學應化系化學學士(1995年9月~1999年6月)
經歷：
  • 國家同步輻射研究中心副研究員(2017年1月~迄今)
  • 國家同步輻射研究中心助研究員 (2010年7月~2016年12月)
  • 柏克萊大學化學系；勞倫斯柏克萊國家實驗室Advanced Light Source博士後研究 (2008年5月~2010年6月)
  • 中研院原分所 博士後研究 (2008年2月~2008年4月)
  • 中研院原分所研究助理 (2002年1月~2006年12月)
負責實驗站：
  • TLS 05B1 軟X光化學光束線
研究領域：
  • 我們已經建造一套包含基質輔助雷射脫附/游離法(MALDI)、垂直加速飛行時間質譜儀(orthogonal acceleration time-of-flight mass spectrometer)的儀器，利用同步輻射光源可調光子能量的軟X光，激發生物分子中特定原子的內層電子至特定的分子軌域，同時達到游離及斷鍵的目的。再以飛行時間質譜儀等，分析其分解碎片的質量和其他特性。利用此方法及其他科學家已經得知一些原子選擇性、位置選擇性的特點，我們將經由質譜取得並歸納生物分子(特別是醣分子)選擇性斷鍵的特性，再經過一連串對生物分子的研究後，以所得之性質協助決定重要生物大分子如醣分子之化學結構。短期的目標是以研究、偵測較小生物分子或是醣類分子的選擇性斷鍵為主，比較激發不同位置的碳原子或氧原子的質譜，尋找生物分子選擇性斷鍵的質譜特徵。
代表作：
  • •    Yu-Ju Chiang, Wan-Chou Huang, Chou-Hsun Han, Chen-Lin Liu*, Cheng-Cheng Tsai, and Wei-Ping Hu,* “Near-edge X-ray Absorption Fine Structure Spectra and Specific Dissociation of Small Peptoid Molecules”, J. Chem. Phys. 160, 074305 (2024).
    •    Meirong Zeng, Chen-Lin Liu, and Kevin R. Wilson*, “Catalytic Coupling of Free Radical Oxidation and Electrophilic Chlorine Addition by Phase-Transfer Intermediates in Liquid Aerosols”, J. Phys. Chem. A, 126, 2959–2965 (2022).
    •    Yao-Te Wang, Yu-Ju Chiang, and Chen-Lin Liu*, “Resolved specific dissociation channel of a core-excited peptide model molecule”, Chem. Phys. Lett., 759, 137967 (2020).
    •    Yu-Ju Chiang, Wan-Chou Huang, Chi-Kung Ni, Chen-Lin Liu*, Cheng-Cheng Tsai, and Wei-Ping Hu*, “NEXAFS spectra and specific dissociation of oligo-peptide model molecules”, AIP Advances, 9, 085023 (2019).
    •    Yu-Ju Chiang, Yi-Shiue Lin, Huei-Ru Lin, and Chen-Lin Liu*, “Specific Dissociation of Core-Excited Pyrimidine Nucleobases”, Chem. Phys. Lett., 706, 215 - 222 (2018).
    •    Cheng-Cheng Tsai, Jien-Lian Chen, Wei-Ping Hu,* Yi-Shiue Lin, Huei-Ru Lin, Tsai-Yun Lee, Yuan T. Lee, Chi-Kung Ni, and  Chen-Lin Liu*, “Selectivity of Peptide Bond Dissociation on Excitation of a Core Electron: Effects of a Phenyl Group”, Chem. Phys. Lett. , 660, 60 - 68 (2016).
    •    Denisia M. Popolan-Vaida, Chen-Lin Liu, Theodora Nah, Kevin R. Wilson, and Stephen R. Leone,* “Reaction of Chlorine Molecules with Unsaturated Submicron Organic Particles”, Z. Phys. Chem., 229, 1521 - 1540 (2015).
    •    Yi-Shiue Lin, Huei-Ru Lin, Wei-Lun Liu, Yuan T. Lee, Chien-Ming Tseng, Chi-Kung Ni, Chen-Lin Liu*, Cheng-Cheng Tsai, Jien-Lian Chen, and Wei-Ping Hu*, “Near-Edge X-ray Absorption Fine Structure Spectra and the Dissociation Following the Core Excitation of Pyrimidine and Purine”, Chem. Phys. Lett. , 636, 146 - 153 (2015).
    •    Yi-Shiue Lin, Cheng-Cheng Tsai, Huei-Ru Lin, Tsung-Lin Hsieh, Jien-Lian Chen, Wei-Ping Hu,* Chi-Kung Ni,* and Chen-Lin Liu*, “Highly Selective Peptide-Bond Dissociation Following Core Electron Excitations”, J. Phys. Chem. A, 119, 6195 - 6202 (2015).
    •    Yi-Shiue Lin, Shu-Yu Lin, Yuan T. Lee, Chien-Ming Tseng, Chi-Kung Ni, Chen-Lin Liu,* Cheng-Cheng Tsai, Jien-Lian Chen, and Wei-Ping Hu*, “Core Excitation, Specific Dissociation and the Effect of the Size of Aromatic Molecules Connected to Oxygen: Phenyl Ether and 1,3-Diphenoxybenzene”, J. Phys. Chem. A, 118, 7803 - 7815 (2014).
    •    Yi-Shiue Lin, Kun-Ta Lu, Yuan T. Lee, Chien-Ming Tseng, Chi-Kung Ni, and Chen-Lin Liu*, “Near-Edge X-ray Absorption Fine Structure Spectra and Site-Selective Dissociation of Phenol”, J. Phys. Chem. A, 118, 1601 - 1609 (2014).
    •    Yi-Shiue Lin, Shu-Yu Lin, Yuan T. Lee, Chien-Ming Tseng, Chi-Kung Ni, Chen-Lin Liu*, Cheng-Cheng Tsai, Jien-Lian Chen, and Wei-Ping Hu*, “Core Excitation, Specific Dissociation and the Effect of the Size of Aromatic Molecules Connected to Oxygen: Phenyl Ether and 1,3-Diphenoxybenzene”, J. Phys. Chem. A, 118, 7803 - 7815 (2014).
    •    S. Soorkia, Chen-Lin Liu, J. D. Savee, S. J. Ferrell, M. Ahmed, S. R. Leone and K. R. Wilson*, “Airfoil sampling of a pulsed Laval beam with tunable vacuum ultraviolet (VUV) synchrotron ionization quadrupole mass spectrometry: Application to low-temperature kinetics and product detection”,Review of Scientific Instruments, 82, 124102 (2011).
    •    C. Koh, Chen-Lin Liu, C. Harmon, D. Strasser, A. Golan, O. Kostko, S. D. Chambreau, G. L.Vaghjiani, and S. R. Leone*, “Soft ionization of thermally evaporated hypergolic ionic liquid aerosols”, J. Phys. Chem. A, 115, 4630 – 4635 (2011).
    •    Chen-Lin Liu, J. D. Smith, D. L. Che, M. Ahmed, S. R. Leone, and K. R. Wilson*, “The Direct Observation of Secondary Radical Chain Chemistry in the Heterogeneous Reaction of Chlorine Atoms with Submicron Squalane Droplets”, Phys. Chem. Chem. Phys., 13, 8993 - 9007 (2011).