About NSRRC / Staff Directory

Molecular Science Group


Name: 劉振霖( Chen-Lin Liu )
EXT.: 7320
E-mail: liu.cl@nsrrc.org.tw
Education:
  • National Tsing Hua University, Hsinchu, Taiwan/Taiwan International Graduate Program, Taipei, Taiwan (Ph. D. in Physical Chemistry) Sep. 2004~Feb. 2008
  • National Chiao Tong University, Hsinchu, Taiwan(M. S. in Chemistry) Sep. 1999 – Jun. 2001
  • National Chiao Tong University, Hsinchu, Taiwan(B. S. in Chemistry) Sep. 1995 – Jun. 1999
Experience:
  • National Synchrotron Radiation Research Center Associate Researcher Fellow (Jan. 2017~now)
  • National Synchrotron Radiation Research Center Assistant Researcher Fellow (July 2010~Dec. 2016)
  • University of California, Berkeley & Lawrence Berkeley National Laboratory Postdoctoral Fellow (May 2008 – Jun. 2010)
  • Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei, Taiwan Postdoctoral Fellow (Feb. 2008 - Apr. 2008)
  • Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei, Taiwan (Five Years Compulsory Military Service in Research Center combined with Ph.D. program) Research Assistant (Jan. 2002 - Dec. 2006)
Endstation:
  • Spokesperson of BL05B1-Soft X-ray Chemistry Beamline
Research Interests:
  • We have built a set that contains matrix-assisted laser desorption / ionization (MALDI) coupled with an orthogonal acceleration time-of-flight mass spectrometer (OA-TOF-MS). Using synchrotron radiation light source with tunable soft X-ray to excite specific atom of a biological molecules, the core electron is stimulate to a particular molecular orbital followed by ionization and fragmentation simultaneously. The composition of the ionic fragments and some other features will be obtained by utilizing time-of-flight mass spectrometer. Using this method and the knowledge of element- and site-specific properties learned by other scientists, we are going to obtain the specificity of selective bond dissociation of bio-molecules (especially carbohydrates) from mass spectra. The analyzed data will be utilized to help determine the structure of important biological macromolecules such as carbohydrates through a series research of biological molecules. The short-term goal is to study the selectivity of bond breaking for small biological molecules/sugar-based molecules and to look for bio-molecular mass characteristics of selective bond breaking by comparing the mass spectra of different positions of excited oxygen atoms or carbon atoms.
Selected Publications:
  • Cheng-Cheng Tsai, Jien-Lian Chen, Wei-Ping Hu,* Yi-Shiue Lin, Huei-Ru Lin, Tsai-Yun Lee, Yuan T. Lee, Chi-Kung Ni, and Chen-Lin Liu*, “Selectivity of Peptide Bond Dissociation on Excitation of a Core Electron: Effects of a Phenyl Group”, Chem. Phys. Lett. , 660, 60 - 68 (2016).
  • Denisia M. Popolan-Vaida, Chen-Lin Liu, Theodora Nah, Kevin R. Wilson, and Stephen R. Leone,* “Reaction of Chlorine Molecules with Unsaturated Submicron Organic Particles”, Z. Phys. Chem., 229, 1521 - 1540 (2015).
  • Yi-Shiue Lin, Huei-Ru Lin, Wei-Lun Liu, Yuan T. Lee, Chien-Ming Tseng, Chi-Kung Ni, Chen-Lin Liu*, Cheng-Cheng Tsai, Jien-Lian Chen, and Wei-Ping Hu*, “Near-Edge X-ray Absorption Fine Structure Spectra and the Dissociation Following the Core Excitation of Pyrimidine and Purine”, Chem. Phys. Lett. , 636, 146 - 153 (2015).
  • Yi-Shiue Lin, Cheng-Cheng Tsai, Huei-Ru Lin, Tsung-Lin Hsieh, Jien-Lian Chen, Wei-Ping Hu,* Chi-Kung Ni,* and Chen-Lin Liu*, “Highly Selective Peptide-Bond Dissociation Following Core Electron Excitations”, J. Phys. Chem. A, 119, 6195 - 6202 (2015).
  • Yi-Shiue Lin, Shu-Yu Lin, Yuan T. Lee, Chien-Ming Tseng, Chi-Kung Ni, Chen-Lin Liu,* Cheng-Cheng Tsai, Jien-Lian Chen, and Wei-Ping Hu*, “Core Excitation, Specific Dissociation and the Effect of the Size of Aromatic Molecules Connected to Oxygen: Phenyl Ether and 1,3-Diphenoxybenzene”, J. Phys. Chem. A, 118, 7803 - 7815 (2014).
  • Yi-Shiue Lin, Kun-Ta Lu, Yuan T. Lee, Chien-Ming Tseng, Chi-Kung Ni, and Chen-Lin Liu*, “Near-Edge X-ray Absorption Fine Structure Spectra and Site-Selective Dissociation of Phenol”, J. Phys. Chem. A, 118, 1601 - 1609 (2014).
  • Yi-Shiue Lin, Shu-Yu Lin, Yuan T. Lee, Chien-Ming Tseng, Chi-Kung Ni, Chen-Lin Liu*, Cheng-Cheng Tsai, Jien-Lian Chen, and Wei-Ping Hu*, “Core Excitation, Specific Dissociation and the Effect of the Size of Aromatic Molecules Connected to Oxygen: Phenyl Ether and 1,3-Diphenoxybenzene”, J. Phys. Chem. A, 118, 7803 - 7815 (2014).
  • S. Soorkia, Chen-Lin Liu, J. D. Savee, S. J. Ferrell, M. Ahmed, S. R. Leone and K. R. Wilson*, “Airfoil sampling of a pulsed Laval beam with tunable vacuum ultraviolet (VUV) synchrotron ionization quadrupole mass spectrometry: Application to low-temperature kinetics and product detection”, Review of Scientific Instruments, 82, 124102 (2011).
  • C. Koh, Chen-Lin Liu, C. Harmon, D. Strasser, A. Golan, O. Kostko, S. D. Chambreau, G. L.Vaghjiani, and S. R. Leone*, “Soft ionization of thermally evaporated hypergolic ionic liquid aerosols”, J. Phys. Chem. A, 115, 4630 – 4635 (2011).
  • Chen-Lin Liu, J. D. Smith, D. L. Che, M. Ahmed, S. R. Leone, and K. R. Wilson*, “The Direct Observation of Secondary Radical Chain Chemistry in the Heterogeneous Reaction of Chlorine Atoms with Submicron Squalane Droplets”, Phys. Chem. Chem. Phys., 13, 8993 - 9007 (2011).
  • Chen-Lin Liu, C. L. Huang, C. K. Ni, N. Ohashi, and J. T. Hougen, “Analysis and fit of the high-resolution spectrum of the 1Au– 1Ag LIF spectrum of the two-equivalent-top molecule biacetyl”, Journal of Molecular Spectroscopy 256, 198 (2009).
  • Chen-Lin Liu, H. C. Hsu, Y. C. Hsu, and C. K. Ni, Energy transfer of highly vibrationally excited naphthalene Ⅲ: Rotation effects, J. Chem. Phys. 128, 164316 (2008).
  • Chen-Lin Liu, H. C. Hsu, Y. C. Hsu, and C. K. Ni, Energy transfer of highly vibrationally excited naphthalene. II. Vibrational energy dependence and isotope and mass effects, J. Chem. Phys. 128, 124320 (2008).
  • Chen-Lin Liu, H. C. Hsu, Y. C. Hsu, and C. K. Ni, Energy transfer of highly vibrationally excited naphthalene I: Translational collision energy dependence, J. Chem. Phys. 127, 104311 (2007).
  • Chen-Lin Liu, H. C. Hsu, J. J. Lyu, and C. K. Ni, Energy transfer of highly vibrationally excited azulene. Ⅲ. Collisions between azulene and argon, J. Chem. Phys. 125, 204309 (2006).
  • Chen-Lin Liu, H. C. Hsu, J. J. Lyu, and C. K. Ni, Energy transfer of highly vibrationally excited azulene: Collisions between azulene and krypton, J. Chem. Phys. 124, 54302 (2006).
  • Chen-Lin Liu, H. C. Hsu, J. J. Lyu, and C. K. Ni, Supercollisions and energy transfer of highly vibrationally excited molecules, J. Chem. Phys. 123, 131102 (2005) (Communication).
  • Chen-Lin Liu, H. C. Hsu, and C. K. Ni, Time-sliced ion imaging study of I2 and I2+ photolysis at 532 nm, Phys. Chem. Chem. Phys., 7, 2151 (2005) (Cover Article).
  • Chen-Lin Liu, H. C. Hsu, and C. K. Ni, Inside front cover of Phys. Chem. Chem. Phys., 7, 2086 (2005)