About NSRRC / Organization

Scientific Research Division > Life Science Group

The research interests of life science are:

  • Synchrotron X-ray protein crystallography, molecular biophysics, structural biology and proteomics (Dr. Chun-Jung Chen). The major research is to study crystal structure and functional relationship of various proteins, including metalloproteins, virus, membrane proteins, enzymes, protein-DNA/RNA complex, and functional important proteins related to drug discovery by Protein Crystallography, X-ray Absorption Fine Structure (XAFS), Circular Dichroism (CD) and Small Angle X-ray Scattering (SAXS).
  • To develop high-resolution microscopic techniques for revealing detailed structures of biological samples (Dr. Su-Yu Chiang). We have implemented a structured illumination (SI) based fluorescence imaging system to provide doubled resolution than the diffraction limit. Now, we are working on the developments of coherent SI imaging for native samples without labelling fluorophores and correlated SI-fluorescence microscopy (SIFM) with soft x-ray tomography at Taiwan photon source (TPS) for bio-medical research.
  • The membrane biophysics and related biology including protein-membrane interaction, drug-membrane interaction and bio-materials (Dr. Ming-Tao Lee). Highlights of our research include developing the X-ray scattering/diffraction methods for membrane structures and the method of giant uniamellar vesicles (GUVs) on the interactions between bio-molecules and membranes.
English NameResearch Interests
Ming-Tao Lee#
  • Bio-membrane structure
  • Protein-membrane interaction
  • Membrane-protein structure
  • Bio-material
Yao-Chang Lee
  • Spokesperson of Infrared Beamline and Infrared Microspectroscopy Endstation
Chun-Jung Chen
  • Protein Crystallography
  • Structural Biology
  • Structural Proteomics
  • Biophysics
Pei-Yu Huang
  • Study of the innovative method of wax physisorption kinetics (WPK) for detecting altered glycosylation for early detection of cancer.
  • Using synchrotron-based FTIR imaging for diagnosing chronic disease and assessing transplanted tissue.
  • Vibrational spectroscopy of fossil using synchrotron-based FTIR microspectroscopy and Confocal Raman microscopy.
Yen-Chieh Huang
  • Genetic Engineering
  • Biochemistry of Protein
  • Structural Biology
Chun-Chieh Wang
# Group Leader
* Fixed-term Employee