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Education：
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- B.S. in Physics, National Central University, Taiwan. (1988-1992)
- Ph. D. in Physics, National Central University, Taiwan. (1999-2004)
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Experience：
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- Associate Scientist at NSRRC (2014-present)
- Joint Associate Professor at National Central University, Taiwan (2014-present)
- Assistant Scientist at NSRRC (2005-2013)
- Joint Assistant Professor at National Central University, Taiwan (2009-2014)
- Postdoctoral studies at National Central University, Taiwan (2004-2005)
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Selected Publications：
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- A David Tzu-Wei Wang, Yi-Chien Tiffany Tang, Chun-Ting Kuo, Yun-Ting Yu, Eric H.-L. Chen, Ming-Tao Lee, Ruei-Fong Tsai, Hung-Ying Chen, Yun-Wei Chiang*, and Rita P.-Y. Chen*. (2023) Cholesterol twists the transmembrane Di-Gly region of amyloid-precursor protein. PNAS Nexus. 2, 1-9.
- Ting-Wei Hsu, Ching-Hsun Yang, Chun-Jen Su*, Yin-Tzu Huang, Yi-Qi Yeh, Kuei-Fen Liao, Tien-Chang Lin, Orion Shih, Ming-Tao Lee, An-Chung Su and U-Ser Jeng*. (2023) Revealing cholesterol effects on PEGylated HSPC liposomes using AF4-MALS and simultaneous small- and wide-angle X-ray scattering. Journal of Applied Crystallography. 56, 988-993.
- Yu-Yung Chang, Meng-Hsuan Hsieh, Yen-Chieh Huang, Chun-Jung Chen, and
Ming-Tao Lee*. (2022) Conformational Changes of -Crystallin Proteins Induced by Heat Stress. Int. J. Mol. Sci. 23, 9347.
- Ming-Tao Lee, Wei-Chin Hung, and Huey W. Huang (2019). Rhombohedral trap for studying molecular oligomerization in membranes: application to daptomycin. Soft Matter, 15, 4326-4333.
- Ming-Tao Lee, Pei-Yin Yang, Nicholas E. Charron, Meng-Hsuan Hsieh, Yu-Yung Chang, and Huey W. Huang* (2018). Comparison of the Effects of Daptomycin on Bacterial and Model Membranes. Biochemistry, 57, 5629-5639.
- Meng-Hsuan Hsieh, Po-Tsang Huang, Horng-Huei Liou, Po-Huang Liang, Pei-Ming Chen, Stephen A. Holt, Isaac Furay Yu, Michael James, Yu-Shuan Shiau,
Ming-Tao Lee*, Tsang-Lang Lin*, and Kuo-Long Lou* (2018). The Penetration Depth for Hanatoxin Partitioning into the Membrane Hydrocarbon Core Measured with Neutron Reflectivity. Langmuir, 34, 9036-9046.
- Ming-Tao Lee*, Biophysical characterization of peptide–membrane interactions. Advances in Physics: X 3, 1408428 (2018).
- Ming-Tao Lee, Wei-Chin Hung, Meng-Hsuan Hsieh, Hsiung Chen, Yu-Yung Chang, Huey W. Huang*, Molecular State of the Membrane-Active Antibiotic Daptomycin. Biophys. J. 113, 82-90 (2017).
- Meng-Hsuan Hsieh, Yu-Shuan Shiau, Horng-Huei Liou, U-Ser Jeng, Ming-Tao Lee*, and Kuo-Long Lou*, Measurement of Hanatoxin-induced Membrane Thinning with Lamellar X-ray Diffraction (LXD). Langmuir 33, 2885-2889 (2017).
- Wei-Chin Hung, Ming-Tao Lee, Hsien Chung, Yi-Ting Sun, Hsiung Chen, Nicholas E. Charron, and Huey W. Huang*, Comparative Study of the Condensing Effects of Ergosterol and Cholesterol. Biophys. J. 110, 2026-2033 (2016).
- Ming-Tao Lee*, Tzu-Lin Sun, Wei-Chin Hung*, and Huey W. Huang*, Process of Inducing Pores in Membranes by Melittin. PNAS 110, 14243-14248 (2013).
- Chun-Jen Su, Shiuan-Shiaou Wu, U-Ser Jeng*, Ming-Tao Lee*, An-Chung Su, Kuei-Fen Liao, Wei-Yu Lin, Yu-Shan Huang, and Chun-Yu Chen, Peptide-induced bilayer thinning structure of unilamellar vesicles and the related binding behavior as revealed by X-ray scattering. BBA-Biomembranes 1828, 528-534 (2013).
- Ming-Tao Lee, Wei-Chin Hung, Fang-Yu Chen and Huey W. Huang, Mechanism and kinetics of pore formation in membranes by water-soluble amphipathic peptides, PNAS 105, 5087-5092 (2008).
- Wei-Chin Hung, Fang-Yu Chen, Chang-Chun Lee, Yen Sun, Ming-Tao Lee and Huey W. Huang, (2008) Membrane Thinning Effect of Curcumin, Biophys. J. 94, 4331-4338.
- Ming-Tao Lee, Wei-Chin Hung, Fang-Yu Chen and Huey W. Huang (2008) Mechanism and kinetics of pore formation in membranes by water-soluble amphipathic peptides, PNAS 105, 5087-5092.
- Wei-Chin Hung, Ming-Tao Lee, Fang-Yu Chen and Huey W. Huang, (2007) The Condensing Effect of Cholesterol in Lipid Bilayers, Biophys. J. 92, 3960-3967.
- Ming-Tao Lee, Wei-Chin Hung, Fang-Yu Chen and Huey W. Huang (2005) Many-body effect of Antimicrobial peptides: on the correlation between lipid’s spontaneous curvature and pore formation, Biophys. J. 89, 4006-4016.
- Huey W. Huang, Fang-Yu Chen and Ming-Tao Lee (2004) Molecular mechanism of peptide-induced pores in membranes, Phys. Rev. Lett. 92, 198304.
- Ming-Tao Lee, Fang-Yu Chen and Huey W. Huang (2004) Energetics of pore formation induced by membrane active peptides, Biochemistry 43, 3590-3599.
- Fang-Yu Chen, Ming-Tao Lee and Huey W. Huang (2003) Evidence for membrane thinning effect as the mechanism for peptide-induced pore formation, Biophys. J. 84, 3751-3758.
- Fang-Yu Chen, Ming-Tao Lee and Huey W. Huang (2002) Sigmoidal concentration dependence of antimicrobial peptide activities: a case study on alamethicin, Biophys. J. 82, 908-914.
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