0428同步年報-2021-全

Life Science 057 Fig. 2 : Structural comparison of ADPR-bound Poa1p with other ADPR-bound macro domains, including HsTARG1 (PDB code 2L8R), EcYmdb (PDB code 5CB3), OiMacroD (PDB code 5L9K), Ymx7 (PDB code 1TXZ), and HsMacroD2 (PDB code 4IQY) colored green, orange, magenta, slate, salmon and yellow, respectively. [Reproduced from Ref. 5] in regulating cellular O AADPR and ADPR. (Reported by Chun-Hua Hsu, National Taiwan University) This report features the work of Chun-Hua Hsu and his colleagues published in ACS Catal. 11 , 11075 (2021). TPS 05A Protein Microcrystallography TLS 15A1 Biopharmaceuticals Protein Crystallography TLS 13B1 Protein Crystallography • Protein Crystallography • Biological Macromolecules, Protein Structures, Life Science References 1 M. D. Jackson, J. M. Denu, J. Biol. Chem. 277 , 18535 (2002). 2 L. Tong, J. M. Denu, Biochim. Biophys. Acta 1804 , 1617 (2010). 3 D. Chen, M. Vollmar, M. N. Rossi, C. Phillips, R. Krae- henbuehl, D. Slade, P. V. Mehrotra, F. v. Delft, S. K. Crosthwaite, O. Gileadi, J. M. Denu, I. Ahel, J. Biol. Chem. 286 , 13261 (2011). 4 L. A. Rafty, M. T. Schmidt, A. L. Perraud, A. M. Scharen- berg, J. M. Denu, J. Biol. Chem. 277 , 47114 (2002). 5 Y. C. Chiu, M. C. Tseng, C. H. Hsu, ACS Catal. 11 , 11075 (2021).