0428同步年報-2021-全

Appendix 153 Elucidation of a Urate Oxidase from Deinococcus Radiodurans for Hyperuricemia and Gout Therapy”, Int. J. Mol. Sci. 22 , 5611 (2021). ◎ Y.-C. Chiu, M.-C. Tseng, and C.-H. Hsu*( 徐駿森 ), “Expanding the Substrate Specificity of Macro Domains toward 3”, ACS Catalysis 11 , 11075 (2021). • S.-H. Choi, B. Jeon, N. Kim, H.-H. Wu, T.-P. Ko, M. W. Ruszczycky, E. A. Isiorho, Y.-N. Liu, A. T. Keatinge-Clay, M.-D. Tsai, and H.-W. Liu*, “Evidence for an Enzyme-catalyzed Rauhut-currier Reaction during the Biosynthesis of Spinosyn A”, J. Am. Chem. Soc. 143 , 20291 (2021). • L. Dai, L. Qin, Y. Hu, J.-W. Huang, Z. Hu, J. Min, Y. Sun*( 孫媛霞 ), and R.-T. Guo*( 郭瑞庭 ), “Structural Dissection of Unnatural Ginsenoside- biosynthetic UDP-glycosyltransferase Bs-YjiC from Bacillus Sbtilis for Substrate Promiscuity”, Biochem. Biophy. Res. Co. 534 , 73 (2021). • H.-H. Guan, Y.-H. Huang, E.-S. Lin, C.-J. Chen*( 陳俊榮 ), and C.-Y. Huang*( 黃晟洋 ), “Plumbagin, a Natural Product with Potent Anticancer Activities, Binds to and Inhibits Dihydroorotase, a Key Enzyme in Pyrimidine Biosynthesis”, Int. J. Mol. Sci. 22 , 6861 (2021). • H.-H. Guan, Y.-H. Huang, E.-S. Lin, C.-J. Chen*( 陳俊榮 ), and C.- Y. Huang*( 黃晟洋 ), “Structural Basis for the Interaction Modes of Dihydroorotase with the Anticancer Drugs 5-fluorouracil and 5-aminouracil”, Biochem. Biophy. Res. Co. 551 , 33 (2021). • H.-H. Guan, Y.-H. Huang, E.-S. Lin, C.-J. Chen*( 陳俊榮 ), and C.-Y. Huang*( 黃晟洋 ), “Structural Analysis of Saccharomyces Cerevisiae Dihydroorotase Reveals Molecular Insights into the Tetramerization Mechanism”, Molecules 26 , 7249 (2021). • H.-H. Guan, Y.-H. Huang, E.-S. Lin, C.-J. Chen*( 陳俊榮 ), and C.-Y. Huang*( 黃晟洋 ), “Complexed Crystal Structure of Saccharomyces Cerevisiae Dihydroorotase with Inhibitor 5-fluoroorotate Reveals a New Binding Mode”, Bioinorg. Chem. Appl. 2021 , 2572844 (2021). • J.-Y. Hong, S.-C. Lin, B.-J. Kuo, and Y.-C. Lo*( 羅玉枝 ), “Structural and Biochemical Basis for Higher-order Assembly between A20-binding Inhibitor of NF-κB 1(ABIN1) and M1-linked Ubiquitins”, J. Mol. Biol. 433 , 167116 (2021). • K.-F. Huang, J.-S. Huang, M.-L. Wu, W.-L. Hsieh, K.-C. Hsu, H.-L. Hsu, T.-P. Ko, and A. H.-J. Wang*( 王惠鈞 ), “A Unique Carboxylic-acid HydrogenBond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes”, J. Mol. Biol. 433 , 166960 (2021). ◎ C.-R. Jhan, R. Satange, S.-C. Wang, J.-Y. Zeng, Y.-C. Horng, P. Jin, S. Neidle, and M.-H. Hou*( 侯明宏 ), “Targeting the ALS/FTD-associated A-DNA Kink with Anthracene-based Metal Complex Causes DNA Backbone Straightening and Groove Contraction”, Nucleic Acids Res. 49 , 9526 (2021). • T.-P. Ko, Y.-C. Wang, C.-L. Tsai, C.-S. Yang, M.-H. Hou, and Y. Chen* ( 陳曄 ), “Crystal Structure and Functional Implication of a Bacterial Cyclic AMP-AMP-GMP Synthetase”, Nucleic Acids Res. 49 , 4725 (2021). • L.-C. Lee, Y.-H. Peng, H.-H. Chang, T. Hsu, C.-T. Lu, C.-H. Huang, C.-C. Hsueh, F.-C. Kung, C.-C. Kuo*( 郭靜娟 ), W.-T. Jiaang*( 蔣維棠 ), and S.-Y. Wu*( 伍素瑩 ), “Xanthine Derivatives Reveal an Allosteric Binding Site in Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2)”, J. Med. Chem. 64 , 11288 (2021). • H.-Y. Lin, C.-Y. Chen, T.-C. Lin, L.-F. Yeh, W.-C. Hsieh, S. Gao, P. Burnouf, B.-M. Chen, T.-J. Hsieh, P. Dashnyam, Y.-H. Kuo, Z. Tu, S. R. Roffler*, and C.-H. Lin*( 林俊宏 ), “Entropy-driven Binding of Gut Bacterial β-glucuronidase Inhibitors Ameliorates Irinotecan-induced Toxicity”, Commun. Biol. 4 , 280 (2021). • M.-H. Lin, C.-C. Cho, Y.-C. Chiu, C.-Y. Chien, Y.-P. Huang, C.-F. Chang, and C.-H. Hsu*( 徐駿森 ), “Elucidating the Tunability of Binding Behavior for the MERS-CoV Macro Domain with NAD Metabolites”, Commun. Biol. 4 , 123 (2021). • W. Liu, C. Ma, W. Liu, Y. Zheng, C.-C. Chen, A. Liang, X. Luo, Z. Li, W. Ma, Y. Song*( 宋亞囝 ), R.-T. Guo*( 郭瑞庭 ), and T. Zhang*( 張同存 ), “Functional and Structural Investigation of a Novel β-mannanase BaMan113A from Bacillus sp. N16-5”, Int. J. Biol. Macromol. 182 , 899 (2021). • M. Maestre-Reyna, W.-C. Huang, W.-J. Wu, P. K. Singh, R. Hartmann, P.-H. Wang, C.-C. Lee, T. Hikima, M. Yamamoto, Y. Bessho, K. Drescher, M.-D. Tsai, and A. H.-J. Wang*( 王惠鈞 ), “Vibrio Cholerae Biofilm Scaffolding Protein RbmA Shows an Intrinsic, Phosphate-dependent Autoproteolysis Activity”, IUBMB Life 73 , 418 (2021). • C. Peng, Y.-H. Li, C.-W. Yu, Z.-H. Cheng, J.-R. Liu, J.-L. Hsu, L.-W. Hsin, C.-T. Huang, H.-F. Juan, J.-W. Chern, and Y.-S. Cheng*( 鄭貽生 ), “Inhibitor Development of MTH1 via High-throughput Screening with Fragment Based Library and MTH1 Substrate Binding Cavity”, Bioorganic Chem. 110 , 104813 (2021). • S. Pengthaisong, Y. Hua, and J. R. K. Cairns, “Structural Basis for Transglycosylation in Glycoside Hydrolase Family GH116 Glycosynthases”, Arch. Biochem. Biophys. 706 , 108924 (2021). • J. P. Singh, M.-J. Lin, S.-F. Hsu, W. Peti, C.-C. Lee*( 李振中 ), and T.-C. Meng*( 孟子青 ), “Crystal Structure of TCPTP Unravels an Allosteric Regulatory Role of Helix α7 in Phosphatase Activity”, Biochemistry 60 , 3856 (2021). • C.-S. Yang, W.-C. Huang, T.-P. Ko, Y.-C. Wang, A. H.-J. Wang, and Y. Chen*( 陳曄 ), “Crystal Structure of the N-terminal Domain of TagH Reveals a Potential Drug Targeting Site”, Biochem. Biophy. Res. Co. 536 , 1 (2021). • C.-Y. Yen, M.-G. Lin, B.-W. Chen, I. W. Ng, N. Read, A. F. Kabli, C.-T. Wu, Y.-Y. Shen, C.-H. Chen, D. Barillà, Y.-J. Sun*( 孫玉珠 ), and C.-D. Hsiao*( 蕭傳鐙 ), “Chromosome Segregation in Archaea: SegA- and SegB-DNA Complex Structures Provide Insights into Segrosome Assembly”, Nucleic Acids Res. 49 , 13150 (2021). TLS 16A1 BM − Tender X-ray Absorption, Diffraction • G.-S. Chen*( 陳錦山 ), J.-H. Chen, J. Kuo, and H. Niu, “Highly Crystallized Mesoporous Anatase Films with Enhanced Photoactivity Derived from Sputter Deposited TiO 2 -WO 3 Composites: The Positive Role of Sodium”, Appl. Surf. Sci. 563 , 150263 (2021). • Z. Chen, H. Niu, J. Ding, H. Liu, P.-H. Chen, Y.-H. Lu, Y.-R. Lu, W. Zuo, L. Han, Y. Guo*( 郭宇錚 ), S.-F. Hung*( 洪崧富 ), and Y. Zhai*( 翟月明 ), “Unraveling the Origin of Sulfur-doped Fe-N-C Single Atom Catalyst for Enhanced Oxygen Reduction Activity: Effect of Fe-spin State Tuning”, Angew. Chem. Int. Edit. 60 , 25404 (2021). • A.-C. Chu, R. S. Sahu, T.-H. Chou, and Y.-H. Shih*( 施養信 ), “Magnetic Fe 3 O 4 @TiO 2 Nanocomposites to Degrade Bisphenol A, One Emerging Contaminant, Under Visible and Long Wavelength UV Light Irradiation”, J. Environ. Chem. Eng. 9 , 105539 (2021). • M. Ding, C. Cheng, Q. Wei*( 魏湫龍 ), Y. Hu, Y. Yan, K. Dai, J. Mao, J. Guo, L. Zhang*( 張亮 ), and L. Mai*( 麥立強 ), “Carbon Decorated Li 3 V 2 (PO 4 ) 3 for High-rate Lithium-ion Batteries: Electrochemical Performance and Charge Compensation Mechanism”, J. Energy Chem. 53 , 124 (2021). • G. D. Dwivedi*, S. M. Kumawat, W. S. Shyu, Y. H. Chien, P. F. Su, Z. H. Huang, S. C. Haw, J. M. Chen, H. Chou*( 周雄 ), and S. Chatterjee*, “Correlating X-ray Absorption Spectra and Ultraviolet Photoelectron Spectra to Understand Magnetic and Transport Properties of Charge- ordered Perovskite Manganites”, Appl. Surf. Sci. 569 , 151131 (2021). • M.-H. Fang, C. O. M. Mariano, K.-C. Chen, J.-C. Lin, Z. Bao, S. Mahlik, T. Lesniewski, K.-M. Lu, Y.-R. Lu, Y.-J. Wu, H.-S. Sheu, J.-F. Lee, S.-F. Hu* ( 胡淑芬 ), R.-S. Liu*( 劉如熹 ), and J. P. Attfield*, “High-performance NaK 2 Li[Li 3 SiO 4 ] 4 :Eu Green Phosphor for Backlighting Light-emitting Diodes”, Chem. Mater. 33 , 1893 (2021). • R. Guo, Y. He, T. Yu, P. Cheng*( 程鵬 ), J. You, H. J. Lin, C.-T. Chen, T. S. Chan, X. Liu*( 劉宣文 ), and Z. Hu*( 胡志偉 ), “Enhanced Oxygen Evolution Reaction Activity of Flower-like FeOOH via the Synergistic Effect of Sulfur”, Chem. Eng. J. 420 , 127587 (2021). • C.-J. Huang, J.-H. Cheng, W.-N. Su, P. Partovi-Azar, L.-Y. Kuo, M.-C. Tsai, M.-H. Lin, S. P. Jand, T.-S. Chan, N.-L. Wu, P. Kaghazchi*, H. Dai, P. M. Bieker, and B.-J. Hwang*( 黃炳照 ), “Origin of Shuttle-free Sulfurized Polyacrylonitrile in Lithium-Sulfur Batteries”, J. Power Sources