2020同步年報

158 ACTIVITY REPORT 2020 TLS 14A1 BM – IR Microscopy • E. K. Astani, S. Ersali, Y.-C. Lee, P.-J. Lin, Y.-C. Huang, P.-Y. Huang, V. Jafarian, S. Hosseinkhani*, C.-J. Chen*( 陳俊榮 ), “ Determination and Evaluation of Sec- ondary Structure Content Derived from Calcium-induced Conformational Changes in Wild-type and Mutant Mnemiopsin 2 by Synchrotron-based Fourier-transform Infrared Spectroscopy ”, BBA-Proteins Proteomics 1868 , 140528 (2020). • J. Y.-S. Chen, Y.-C. Lee, and B. A. Walther*, “ Microplastic Contamination of Three Commonly Consumed Seafood Species from Taiwan: A Pilot Study ”, Sustainability 12 , 9543 (2020). ◎ Y.-L. Cho, Y.-C. Lee, L.-C. Hsu, C.-C. Wang, P.-C. Chen, S.-L. Liu, H.-Y. Teah, Y.-T. Liu*( 劉雨庭 ), and Y.-M. Tzou*( 鄒裕民 ), “ Molecular Mechanisms for Pb Removal by Cyanidiales: a Potential Biomaterial Applied in Thermo-acidic Condi- tions ”, Chem. Eng. J. 401 , 125828 (2020). • C.-L. Huang, P.-Y. Wang, and Y.-Y. Li*( 李元堯 ), “ Fabrication of Electrospun CO 2 Adsorption Membrane for Zinc-air Battery Application ”, Chem. Eng. J. 395 , 125031 (2020). ◎ I.-M. Lin, C.-M. Chou, M.-C. Li, R.-H. Guo, C.-K. Lee, H.-J. Li, Y.-W. Chiang* ( 蔣酉旺 ), Y.-H. Lin, Y.-C. Lee, C.-J. Su, U.-S. Jeng, and W.-T. Chuang*( 莊偉綜 ), “ Superhelices with Tunable Twisting Power Directed from Supramolecular Pairing of Focal Asymmetry in Achiral Dendron-jacketed Block Copolymers ”, J. Mater. Chem. C 8 , 1923 (2020). • Y.-T. Weng, J. Rathod, B. Liang*( 梁碧清 ), C.-C. Wang, Y. Iizuka, N. Tamura, C.-L. Chen, and Y.-C. Lee, “ Black Carbon Enriches Short-range-order Ferrihydrite in Amazonian Dark Earth: Interplay Mechanism and Environmental Implications ”, Sci. Total Environ. 725 , 138195 (2020). TLS 15A1 Biopharmaceuticals Protein Crystallography • K. Adhikari, I.-W. Lo, C.-L. Chen, Y.-L. Wang, K.-H. Lin, S. M. Zadeh, R. Rattinam, Y.-S. Li, C.-J. Wu, and T.-L. Li*( 李宗璘 ), “ Chemoenzymatic Synthesis and Biologi- cal Evaluation for Bioactive Molecules Derived from Bacterial Benzoyl Coenzyme A Ligase and Plant Type III Polyketide Synthase ”, Biomolecules 10 , 738 (2020). • E. K. Astani, N.-C. Chen, Y.-C. Huang, S. Ersali, P.-J. Lin, H.-H. Guan, C.-C. Lin, P. Chuankhayan, and C.-J. Chen*( 陳俊榮 ), “ Characterization of Dimeric Interac- tions within Protrusion-Domain Interfaces of Parallel and X-shaped Conformations of Macrobrachium Rosenbergii Nodavirus: A Theoretical Study Using the DFT Method along with QTAIM and NBO Analyses ”, ACS Omega 5 , 3428 (2020). • S.-K. Chen, H.-H. Guan, P.-H. Wu, L.-T. Lin, M.-C. Wu, H.-Y. Chang, N.-C. Chen, C.-C. Lin, P. Chuankhayan, Y.-C. Huang, P.-J. Lin, and C.-J. Chen*( 陳俊榮 ), “ Structural Insights into the Histidine-containing Phosphotransfer Protein and Receiver Domain of Sensor Histidine Kinase Suggest a Complex Model in the Two-component Regulatory System in Pseudomonas Aeruginosa ”, IUCrJ 7 , 934 (2020). ◎ C.-M. Chien, P.-C. Wu, R. Satange, C.-C. Chang, Z.-L. Lai, L. D. Hagler, S. C. Zimmerman*, and M.-H. Hou*( 侯明宏 ), “ Structural Basis for Targeting T: T Mismatch with Triaminotriazine-acridine Conjugate Induces a U-shaped Head- to-Head Four-way Junction in CTG Repeat DNA ”, J. Am. Chem. Soc. 142 , 11165 (2020). ◎ C.-M. Hsieh, C.-Y. Chen, J.-W. Chern, and N.-L. Chan*( 詹迺立 ), “ Structure of Human Phosphodiesterase 5A1 Complexed with Avanafil Reveals Molecular Basis of Isoform Selectivity and Guidelines for Targeting α-helix Backbone Oxygen by Halogen Bonding ”, J. Med. Chem. 63 , 8485 (2020). • S.-H. Hsu, C.-H. Chu, Y.-C. Tian, M.-Y. Chang, L.-F. Chou, Y.-J. Sun, and C.-W. Yang*( 楊智偉 ), “ Crystal Structure of Leptospira Leucine-rich Repeat 20 Reveals a Novel E-cadherin Binding Protein to Induce NGAL Expression in HK2 Cells ”, Biochem. J. 477 , 4313 (2020). • J.-W. Huang, D. Niu, K. Liu, Q. Wang, L. Ma, C.-C. Chen, L. Zhang, W. Liu, S. Zhou, J. Min, S. Wu, Y. Yang*( 楊勇 ), and R.-T. Guo*( 郭瑞庭 ), “ Structure Basis of Non-structural Protein pA151R from African Swine Fever Virus ”, Biochem. Biophy. Res. Co. 532 , 108 (2020). • H.-K. Jiang, Y.-H. Wang, J.-H. Weng, P. Kurkute, C.-L. Li, M.-N. Lee, P.-J. Chen, H.-W. Tseng, M.-D. Tsai, and Y.-S. Wang*( 王彥士 ), “ Probing the Active Site of Deubiquitinase USP30 with Non-canonical Tryptophan Analogues ”, Biochemistry 59 , 2205 (2020). • A. A. Khine, H.-P. Chen, K.-F. Huang*( 黃開發 ), and T.-P. Ko*( 柯子平 ), “ Struc- tural Characterization of Borneol Dehydrogenase from Pseudomonas sp. TCU- HL1 ”, Acta Crystallogr. F 76 , 309 (2020). • C.-H. Lai, C.-C. Chang, H.-C. Chuang, T.-H. Tan, and P.-C. Lyu*( 呂平江 ), “ Struc- tural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases ”, Int. J. Mol. Sci. 21 , 7515 (2020). • C.-C. Lee*( 李政忠 ), Y.-C. Su, T.-P. Ko, L.-L. Lin, C.-Y. Yang, S. S.-C. Chang, S. R. Roffler*, and A. H.-J. Wang*( 王惠鈞 ), “ Structural Basis of Polyethylene Glycol Recognition by Antibody ”, J. Biomed. Sci. 27 , 12 (2020). • J. Li, H.-J. Liao, Y. Tang, J.-L. Huang, L. Cha, T.-S. Lin, J. L. Lee, I. V. Kurnikov, M. G. Kurnikova*, W.-C. Chang*( 張瑋成 ), N.-L. Chan*( 詹迺立 ), and Y. Guo*, “ Epoxidation Catalyzed by the Nonheme Iron(II)-and 2-oxoglutarate-de- pendent Oxygenase, AsqJ: Mechanistic Elucidation of Oxygen Atom Transfer by a Ferryl Intermediate ”, J. Am. Chem. Soc. 142 , 6268 (2020). ◎ C.-C. Lin, Y.-P. Chen, W.-Z. Yang, J. C. K. Shen, and H. S. Yuan*( 袁小琀 ), “ Struc- tural Insights into CpG-specific DNA Methylation by Human DNA Methyltransfer- ase 3B ”, Nucleic Acids Res. 48 , 3949 (2020). • K.-H. Lin, S.-Y. Lyu, H.-W. Yeh, Y.-S. Li, N.-S. Hsu, C.-M. Huang, Y.-L. Wang, H.-W. Shih, Z.-C. Wang, C.-J. Wu, and T.-L. Li*( 李宗璘 ), “ Structural and Chemical Trapping of Flavin-oxide Intermediates Reveals Substrate-directed Reaction Multiplicity ”, Protein Sci. 29 , 1655 (2020). • Y.-H. Peng, F.-Y. Liao, C.-T. Tseng, R. Kuppusamy, A.-S. Li, C.-H. Chen, Y.-S. Fan, S.-Y. Wang, M.-H. Wu, C.-C. Hsueh, J.-Y. Chang, L.-C. Lee, C. Shih, K.-S. Shia, T.- K. Yeh, M.-S. Hung, C.-C. Kuo, J.-S. Song, S.-Y. Wu*( 伍素瑩 ), and S.-H. Ueng* ( 翁紹華 ), “ Unique Sulfur-aromatic Interactions Contribute to the Binding of Potent Imidazothiazole Indoleamine 2,3-Dioxygenase Inhibitors ”, J. Med. Chem. 63 , 1642 (2020). • H. Sun, T.-P. Ko, W. Liu, W. Liu, Y. Zheng, C.-C. Chen*( 陳純琪 ), and R.-T. Guo* ( 郭瑞庭 ), “ Structure of an Antibiotic-synthesizing UDP-glucuronate 4-epimerase MoeE5 in Complex with Substrate ”, Biochem. Biophy. Res. Co. 521 , 31 (2020). • Y.-C. Wang, W.-H. Yang, C.-S. Yang, M.-H. Hou, C.-L. Tsai, Y.-Z. Chou, M.-C. Hung*( 洪明奇 ), and Y. Chen*( 陳曄 ), “ Structural Basis of SARS-CoV-2 Main Protease Inhibition by a Broad-spectrum Anti-coronaviral Drug ”, Am. J. Cancer Res. 10 , 2535 (2020). • M. Yoshimura, N.-C. Chen, H.-H. Guan, P. Chuankhayan, C.-C. Lin, A. Nakaga- wa, and C.-J. Chen*( 陳俊榮 ), “ Noncrystallographic Symmetry-constrained Map Obtained by Direct Density Optimization ”, Acta Crystallogr. D 76 , 147 (2020). • S. Zhou, T.-P. Ko*( 柯子平 ), J.-W. Huang, W. Liu, Y. Zheng, S. Wu, Q. Wang, Z. Xie, Z. Liu, C.-C. Chen*( 陳純琪 ), and R.-T. Guo*( 郭瑞庭 ), “ Structure of a Gut Microbial Diltiazem-metabolizing Enzyme Suggests Possible Substrate Binding Mode ”, Biochem. Biophy. Res. Co. 527 , 799 (2020). TLS 16A1 BM – Tender X-ray Absorption, Diffraction • K. Baumann*, S. M. Shaheen, Y. Hu, P. Gros, E. Heilmann, M. Morshedizad, J. Wang, S.-L, Wang, J. Rinklebe, and P. Leinweber, “ Speciation and Sorption of Phosphorus in Agricultural Soil Profiles of Redoximorphic Character ”, Environ. Geochem. Health 42 , 3231 (2020). • M. Bhavanari, K.-R. Lee, B. J. Su, D. Dutta, Y.-H. Hung, C.-J. Tseng*( 曾重仁 ), and C.-Y. Su*( 蘇清源 ), “ MoS x on Nitrogen-doped Graphene for High-efficiency Hydrogen Evolution Reaction: Unraveling the Mechanisms of Unique Interfacial Bonding for Efficient Charge Transport and Stability ”, ACS Appl. Mater. Interfaces 12 , 34825 (2020). • T. Billo, I. Shown*, A. K. Anbalagan, T. A. Effendi, A. Sabbah, F.-Y. Fu, C.-M. Chu, W.-Y. Woon, R.-S. Chen, C.-H. Lee*( 李志浩 ), K.-H. Chen*( 陳貴賢 ), and L.-C. Chen*( 林麗瓊 ), “ A Mechanistic Study of Molecular CO 2 Interaction and Adsorp- tion on Carbon Implanted SnS 2 Thin Film for Photocatalytic CO 2 Reduction Activity ”, Nano Energy 72 , 104717 (2020). • S. Cao, T.-S. Chan, Y.-R. Lu, X. Shi, B. Fu, Z. Wu, H. Li, K. Liu, S. Alzuabi, P.