2020同步年報

Appendix 157 Hsia*( 夏國強 ), “ Karyopherin Kap114p-mediated Trans-repression Controls Ribosomal Gene Expression under Saline Stress ”, EMBO Rep. 21 , e48324 (2020). • Y.-T. Liao, S.-J. Lin, T.-P. Ko, C.-Y. Liu, K.-C. Hsu, and H.-C. Wang*( 王皓青 ), “ Structural Insight into the Differential Interactions Between the DNA Mimic Protein SAUGI and Two Gamma Herpesvirus Uracil-DNA Glycosylases ”, Int. J. Biol. Macromol. 160 , 903 (2020). • K.-H. Lin, S.-Y. Lyu, H.-W. Yeh, Y.-S. Li, N.-S. Hsu, C.-M. Huang, Y.-L. Wang, H.-W. Shih, Z.-C. Wang, C.-J. Wu, and T.-L. Li*( 李宗璘 ), “ Structural and Chemical Trapping of Flavin-oxide Intermediates Reveals Substrate-directed Reaction Multiplicity ”, Protein Sci. 29 , 1655 (2020). • M.-H. Lin, P.-C. Kuo, Y.-C. Chiu, Y.-Y. Chang, S.-C. Chen, and C.-H. Hsu*( 徐駿森 ), “ The Crystal Structure of Protein-transporting Chaperone BCP1 from Saccharomy- ces Cerevisiae ”, J. Struct. Biol. 212 , 107605 (2020). • S.-M. Lin, S.-C. Lin, J.-N. Hsu, C.-K. Chang, C.-M. Chien, Y.-S. Wang, H.-Y. Wu, U.- S. Jeng, K. Kehn-Hall, and M.-H. Hou*( 侯宏明 ), “ Structure-Based Stabilization of Non-native Protein-protein Interactions of Coronavirus Nucleocapsid Proteins in Antiviral Drug Design ”, J. Med. Chem. 63 , 3131 (2020). • J. Manissorn, T. Sitthiyotha, J. R. E. Montalban, S. Chunsrivirot, P. Thongnuek, and K. Wangkanont*, “ Biochemical and Structural Investigation of GnnA in the Lipopolysaccharide Biosynthesis Pathway of Acidithiobacillus Ferrooxidans ”, ACS Chem. Biol. 15 , 3235 (2020). • Y.-H. Peng, F.-Y. Liao, C.-T. Tseng, R. Kuppusamy, A.-S. Li, C.-H. Chen, Y.-S. Fan, S.-Y. Wang, M.-H. Wu, C.-C. Hsueh, J.-Y. Chang, L.-C. Lee, C. Shih, K.-S. Shia, T.- K. Yeh, M.-S. Hung, C.-C. Kuo, J.-S. Song, S.-Y. Wu*( 伍素瑩 ), and S.-H. Ueng* ( 翁紹華 ), “ Unique Sulfur-aromatic Interactions Contribute to the Binding of Potent Imidazothiazole Indoleamine 2,3-Dioxygenase Inhibitors ”, J. Med. Chem. 63 , 1642 (2020). • S. Sadotra, Y.-C. Lou, H.-C. Tang, Y.-C. Chiu, C.-H. Hsu*( 徐駿森 ), and C. Chen* ( 陳金榜 ), “ Structural Basis for Promoter DNA Recognition by the Response Regulator OmpR ”, J. Struct. Biol. 213 , 107638 (2020). • C. Songsiriritthigul*, R. Narawongsanont, C. Tantitadapitak, H.-H. Guan, and C.-J. Chen, “ Structure-function Study of AKR4C14, an Aldo-keto Reductase from Thai Jasmine Rice (Oryza sativa L. ssp. indica cv. KDML105) ”, Acta Crystallogr. D 76 , 472 (2020). • Y.-C. C. Tsai, F. Ye, L. Liew, D. Liu, S. Bhushan, Y.-G. Gao*( 高永貴 ), and O. Mueller-Cajar*, “ Insights into the Mechanism and Regulation of the CbbQO-type Rubisco Activase, a MoxR AAA+ ATPase ”, P. Natl. Acad. Sci. USA 117 , 381 (2020). • M. Wieczorek, T.-L. Huang, L. Urnavicius, K.-C. Hsia*( 夏國強 ), and T. M. Kapoor*, “ MZT Proteins Form Multi-faceted Structural Modules in the γ-tubulin Ring Complex ”, Cell Rep. 31 , 107791 (2020). • C.-Y. Wu, I.-C. Hu, Y.-C. Yang, W.-C. Ding, C.-H. Lai, Y.-Z. Lee, Y.-C. Liu, H.-C. Cheng, and P.-C. Lyu*( 呂平江 ), “ An Essential Role of Acetyl Coenzyme A in the Catalytic Cycle of Insect Arylalkylamine N-acetyltransferase ”, Commun. Biol. 3 , 441 (2020). • X. Xiao, S. S. Elsayed, C. Wu, H. U. van der Heul, M. Metsa-Ketela, C. Du, A. E. Prota, C.-C. Chen, W. Liu, R.-T. Guo, J. P. Abrahams, and G. P. van We- zel*, “ Functional and Structural Insights into a Novel Promiscuous Ketoreductase of the Lugdunomycin Biosynthetic Pathway ”, ACS Chem. Biol. 15 , 2529 (2020). • M. Yoshimura, N.-C. Chen, H.-H. Guan, P. Chuankhayan, C.-C. Lin, A. Nakaga- wa, and C.-J. Chen*( 陳俊榮 ), “ Noncrystallographic Symmetry-constrained Map Obtained by Direct Density Optimization ”, Acta Crystallogr. D 76 , 147 (2020). TLS 13C1 SW60 – Protein Crystallography • K. Adhikari, I.-W. Lo, C.-L. Chen, Y.-L. Wang, K.-H. Lin, S. M. Zadeh, R. Rattinam, Y.-S. Li, C.-J. Wu, and T.-L. Li*( 李宗璘 ), “ Chemoenzymatic Synthesis and Biologi- cal Evaluation for Bioactive Molecules Derived from Bacterial Benzoyl Coenzyme A Ligase and Plant Type III Polyketide Synthase ”, Biomolecules 10 , 738 (2020). • S. Aryal, H.-M. Hsu, Y.-C. Lou, C.-H. Chu, J.-H. Tai, C.-H. Hsu*( 徐駿森 ), and C. Chen*( 陳金榜 ), “ N-Terminal Segment of TvCyP2 Cyclophilin from Trichomonas Vaginalis Is Involved in Self-association, Membrane Interaction, and Subcellular Localization ”, Biomolecules 10 , 1239 (2020). • C.-Y. Chen, P.-H. Lin, K.-H. Chen, and Y.-S. Cheng*( 鄭貽生 ), “ Structural Insights into Arabidopsis Ethylene Response Factor 96 with an Extended N-terminal Binding to GCC Box ”, Plant Mol. Biol. 104 , 483 (2020). • S.-C. Chen, S.-P. Wu, Y.-Y. Chang, T.-S. Hwang, T.-H. Lee*( 李宗徽 ), and C.-H. Hsu*( 徐駿森 ), “ Crystal Structure of α-galactosidase from Thermus Thermophilus: Insight into Hexamer Assembly and Substrate Specificity ”, J. Agr. Food Chem. 68 , 6161 (2020). • Y.-C. Chen, S.-P. Chen, J.-Y. Li, P.-C. Chen, Y.-Z. Lee, K.-M. Li, R. Zarivach, Y.-J. Sun, and S.-C. Sue*( 蘇士哲 ), “ Integrative Model to Coordinate the Oligomeriza- tion and Aggregation Mechanisms of CCL5 ”, J. Mol. Biol. 432 , 1143 (2020). • P. Dashnyam, H.-Y. Lin, C.-Y. Chen, S. Gao, L.-F. Yeh, W.-C. Hsieh, Z. Tu, and C.- H. Lin*( 林俊宏 ), “ Substituent Position of Iminocyclitols Determines the Potency and Selectivity for Gut Microbial Xenobiotic-reactivating Enzymes ”, J. Med. Chem. 63 , 4617 (2020). ◎ C.-M. Hsieh, C.-Y. Chen, J.-W. Chern, and N.-L. Chan*( 詹迺立 ), “ Structure of Human Phosphodiesterase 5A1 Complexed with Avanafil Reveals Molecular Basis of Isoform Selectivity and Guidelines for Targeting α-helix Backbone Oxygen by Halogen Bonding ”, J. Med. Chem. 63 , 8485 (2020). • T.-L. Huang, H.-J. Wang, Y.-C. Chang, S.-W. Wang, and K.-C. Hsia*( 夏國強 ), “ Promiscuous Binding of Microprotein Mozart1 to γ-tubulin Complex Mediates Specific Subcellular Targeting to Control Microtubule Array Formation ”, Cell Rep. 31 , 107836 (2020). • J.-Y. Li, Y.-C. Chen, Y.-Z. Lee, C.-H. Huang, and S.-C. Sue*( 蘇士哲 ), “ N-terminal Backbone Pairing Shifts in CCL5- 12 AAA 14 Dimer Interface: Structural Significance of the FAY Sequence ”, Int. J. Mol. Sci. 21 , 1689 (2020). • C.-C. Liao, S. Shankar, W.-C. Pi, C.-C. Chang, G. R. Ahmed, W.-Y. Chen, and K.-C. Hsia*( 夏國強 ), “ Karyopherin Kap114p-mediated Trans-repression Controls Ribosomal Gene Expression under Saline Stress ”, EMBO Rep. 21 , e48324 (2020). • Y.-T. Liao, S.-J. Lin, T.-P. Ko, C.-Y. Liu, K.-C. Hsu, and H.-C. Wang*( 王皓青 ), “ Structural Insight into the Differential Interactions Between the DNA Mimic Protein SAUGI and Two Gamma Herpesvirus Uracil-DNA Glycosylases ”, Int. J. Biol. Macromol. 160 , 903 (2020). • K.-H. Lin, S.-Y. Lyu, H.-W. Yeh, Y.-S. Li, N.-S. Hsu, C.-M. Huang, Y.-L. Wang, H.-W. Shih, Z.-C. Wang, C.-J. Wu, and T.-L. Li*( 李宗璘 ), “ Structural and Chemical Trapping of Flavin-oxide Intermediates Reveals Substrate-directed Reaction Multiplicity ”, Protein Sci. 29 , 1655 (2020). • Y.-H. Peng, F.-Y. Liao, C.-T. Tseng, R. Kuppusamy, A.-S. Li, C.-H. Chen, Y.-S. Fan, S.-Y. Wang, M.-H. Wu, C.-C. Hsueh, J.-Y. Chang, L.-C. Lee, C. Shih, K.-S. Shia, T.- K. Yeh, M.-S. Hung, C.-C. Kuo, J.-S. Song, S.-Y. Wu*( 伍素瑩 ), and S.-H. Ueng* ( 翁紹華 ), “ Unique Sulfur-aromatic Interactions Contribute to the Binding of Potent Imidazothiazole Indoleamine 2,3-Dioxygenase Inhibitors ”, J. Med. Chem. 63 , 1642 (2020). • S.-W. Shen, Y.-C. Wei, F.-Y. Fu, K.-J. Chou, S.-F. Wang, L.-W. Fu, W.-T. Chuang, M.-L. Tsai, M.-H. Chen, Y. Chi*( 季昀 ), P.-T. Chou*( 周必泰 ), and C.-I. Wu* ( 吳志毅 ), “ Interlayer Charge Transfer Coupled with Acoustic Phonon in Organic/ Inorganic van der Waals Stacked Heterostructures: Self-assembled Pt(II) Complex on a PtSe 2 Monolayer ”, J. Phys. Chem. C 124 , 25538 (2020). • C. Songsiriritthigul*, N. Nualkaew, J. Ketudat-Cairns, and C.-J. Chen, “ The Crys- tal Structure of Benzophenone Synthase from Garcinia Mangostana L. Pericarps Reveals the Basis for Substrate Specificity and Catalysis ”, Acta Crystallogr. F 76 , 597 (2020). • H. Sun, T.-P. Ko, W. Liu, W. Liu, Y. Zheng, C.-C. Chen*( 陳純琪 ), and R.-T. Guo* ( 郭瑞庭 ), “ Structure of an Antibiotic-synthesizing UDP-glucuronate 4-epimerase MoeE5 in Complex with Substrate ”, Biochem. Biophy. Res. Co. 521 , 31 (2020). • M. Wieczorek, T.-L. Huang, L. Urnavicius, K.-C. Hsia*( 夏國強 ), and T. M. Kapoor*, “ MZT Proteins Form Multi-faceted Structural Modules in the γ-tubulin Ring Complex ”, Cell Rep. 31 , 107791 (2020). • C.-Y. Wu, I.-C. Hu, Y.-C. Yang, W.-C. Ding, C.-H. Lai, Y.-Z. Lee, Y.-C. Liu, H.-C. Cheng, and P.-C. Lyu*( 呂平江 ), “ An Essential Role of Acetyl Coenzyme A in the Catalytic Cycle of Insect Arylalkylamine N-acetyltransferase ”, Commun. Biol. 3 , 441 (2020).