2020同步年報

144 ACTIVITY REPORT 2020 Note: 1. Asterisks (*) indicate corresponding authors. Their Chinese names are shown in parentheses if applicable. 2. Publications are sorted by endstation and listed in alphabetic order according to the last name of the first author. 3. Publications using more than one beamline are listed in corre- sponding beamline sections . 4. Publications marked ◎ are selected to report in the section of Research Highlights. TPS 05A Protein Microcrystallography • K. Adhikari, I.-W. Lo, C.-L. Chen, Y.-L. Wang, K.-H. Lin, S. M. Zadeh, R. Rattinam, Y.-S. Li, C.-J. Wu, and T.-L. Li*( 李宗璘 ), “ Chemoenzymatic Synthesis and Biologi- cal Evaluation for Bioactive Molecules Derived from Bacterial Benzoyl Coenzyme A Ligase and Plant Type III Polyketide Synthase ”, Biomolecules 10 , 738 (2020). • E. K. Astani, N.-C. Chen, Y.-C. Huang, S. Ersali, P.-J. Lin, H.-H. Guan, C.-C. Lin, P. Chuankhayan, and C.-J. Chen*( 陳俊榮 ), “ Characterization of Dimeric Interac- tions within Protrusion-Domain Interfaces of Parallel and X-shaped Conformations of Macrobrachium Rosenbergii Nodavirus: A Theoretical Study Using the DFT Method along with QTAIM and NBO Analyses ”, ACS Omega 5 , 3428 (2020). • C.-C. Chen, J. Xue, W. Peng, B. Wang, L. Zhang, W. Liu, T.-P. Ko, J.-W. Huang, S. Zhou, J. Min, L. Ma, L. Dai*( 戴隆海 ), R.-T. Guo*( 郭瑞庭 ), and X. Yu* ( 喻雪婧 ), “ Structural Insights into Thebaine Synthase 2 Catalysis ”, Biochem. Biophy. Res. Co. 529 , 156 (2020). • C.-Y. Chen, Y.-T. Tu, J.-C. Hsu, H.-C. Hung, T.-C. Liu, Y.-H. Lee, C.-C. Chou, Y.-S. Cheng*( 鄭貽生 ), and K. Wu*( 吳克強 ), “ Structure of Arabidopsis Histone Deacetylase15 ”, Plant Physiol. 184 , 1585 (2020). • S.-K. Chen, H.-H. Guan, P.-H. Wu, L.-T. Lin, M.-C. Wu, H.-Y. Chang, N.-C. Chen, C.-C. Lin, P. Chuankhayan, Y.-C. Huang, P.-J. Lin, and C.-J. Chen*( 陳俊榮 ), “ Structural Insights into the Histidine-containing Phosphotransfer Protein and Receiver Domain of Sensor Histidine Kinase Suggest a Complex Model in the Two-component Regulatory System in Pseudomonas Aeruginosa ”, IUCrJ 7 , 934 (2020). • Y.-C. Chen, Y.-T. Chang, C.-Y. Chen, J.-H. Shiu, C.-H. Cheng, C.-H. Huang, J.-F. Chen, and W.-J. Chuang*( 莊偉哲 ), “ Structural Insight into Integrin Recognition and Anticancer Activity of Echistatin ”, Toxins 12 , 709 (2020). ◎ C.-M. Chien, P.-C. Wu, R. Satange, C.-C. Chang, Z.-L. Lai, L. D. Hagler, S. C. Zimmerman*, and M.-H. Hou*( 侯明宏 ), “ Structural Basis for Targeting T: T Mismatch with Triaminotriazine-acridine Conjugate Induces a U-shaped Head- to-Head Four-way Junction in CTG Repeat DNA ”, J. Am. Chem. Soc. 142 , 11165 (2020). • T. Hayashi, S. Yasuda, K. Suzuki, T. Akiyama, K. Kanehara, K. Kojima, M. Tanabe, R. Kato, T. Senda, Y. Sudo, T. Murata*, and M. Kinoshita*, “ How Does a Microbial Rhodopsin RxR Realize Its Exceptionally High Thermostability with the Proton-pumping Function Being Retained? ”, J. Phys. Chem. B 124 , 990 (2020). • B. S. Heater, Z. Yang, M. M. Lee, and M. K. Chan*( 陳文博 ), “ In Vivo Enzyme Entrapment in a Protein Crystal ”, J. Am. Chem. Soc. 142 , 9879 (2020). • J.-W. Huang, D. Niu, K. Liu, Q. Wang, L. Ma, C.-C. Chen, L. Zhang, W. Liu, S. Zhou, J. Min, S. Wu, Y. Yang*( 楊勇 ), and R.-T. Guo*( 郭瑞庭 ), “ Structure Basis of Non-structural Protein pA151R from African Swine Fever Virus ”, Biochem. Biophy. Res. Co. 532 , 108 (2020). • T.-L. Huang, H.-J. Wang, Y.-C. Chang, S.-W. Wang, and K.-C. Hsia*( 夏國強 ), “ Promiscuous Binding of Microprotein Mozart1 to γ-tubulin Complex Mediates Specific Subcellular Targeting to Control Microtubule Array Formation ”, Cell Rep. 31 , 107836 (2020). • H.-K. Jiang, Y.-H. Wang, J.-H. Weng, P. Kurkute, C.-L. Li, M.-N. Lee, P.-J. Chen, H.-W. Tseng, M.-D. Tsai, and Y.-S. Wang*( 王彥士 ), “ Probing the Active Site of Deubiquitinase USP30 with Non-canonical Tryptophan Analogues ”, Biochemistry 59 , 2205 (2020). • L. Juniar, H. Tanaka, K. Yoshida, T. Hisabori, and G. Kurisu*, “ Structural Basis for Thioredoxin Isoform-based Fine-tuning of Ferredoxin-thioredoxin Reductase Activity ”, Protein Sci. 29 , 2538 (2020). • C.-H. Lai, C.-C. Chang, H.-C. Chuang, T.-H. Tan, and P.-C. Lyu*( 呂平江 ), “ Struc- tural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases ”, Int. J. Mol. Sci. 21 , 7515 (2020). • C.-C. Lee*( 李政忠 ), Y.-C. Su, T.-P. Ko, L.-L. Lin, C.-Y. Yang, S. S.-C. Chang, S. R. Roffler*, and A. H.-J. Wang*( 王惠鈞 ), “ Structural Basis of Polyethylene Glycol Recognition by Antibody ”, J. Biomed. Sci. 27 , 12 (2020). • J. Li, H.-J. Liao, Y. Tang, J.-L. Huang, L. Cha, T.-S. Lin, J. L. Lee, I. V. Kurnikov, M. G. Kurnikova*, W.-C. Chang*, N.-L. Chan*( 詹迺立 ), and Y. Guo*, “ Epoxidation Catalyzed by the Nonheme Iron(II)-and 2-oxoglutarate-dependent Oxygenase, AsqJ: Mechanistic Elucidation of Oxygen Atom Transfer by a Ferryl Intermediate ”, J. Am. Chem. Soc. 142 , 6268 (2020). • J.-Y. Li, Y.-C. Chen, Y.-Z. Lee, C.-H. Huang, and S.-C. Sue*( 蘇士哲 ), “ N-terminal Backbone Pairing Shifts in CCL5- 12 AAA 14 Dimer Interface: Structural Significance of the FAY Sequence ”, Int. J. Mol. Sci. 21 , 1689 (2020). • C.-C. Liao, S. Shankar, W.-C. Pi, C.-C. Chang, G. R. Ahmed, W.-Y. Chen, and K.-C. Hsia*( 夏國強 ), “ Karyopherin Kap114p-mediated Trans-repression Controls Ribosomal Gene Expression under Saline Stress ”, EMBO Rep. 21 , e48324 (2020). ◎ C.-C. Lin, Y.-P. Chen, W.-Z. Yang, J. C. K. Shen, and H. S. Yuan*( 袁小琀 ), “ Struc- tural Insights into CpG-specific DNA Methylation by Human DNA Methyltransfer- ase 3B ”, Nucleic Acids Res. 48 , 3949 (2020). • K.-H. Lin, S.-Y. Lyu, H.-W. Yeh, Y.-S. Li, N.-S. Hsu, C.-M. Huang, Y.-L. Wang, H.-W. Shih, Z.-C. Wang, C.-J. Wu, and T.-L. Li*( 李宗璘 ), “ Structural and Chemical Trapping of Flavin-oxide Intermediates Reveals Substrate-directed Reaction Multiplicity ”, Protein Sci. 29 , 1655 (2020). • M.-H. Lin, S.-C. Chang, Y.-C. Chiu, B.-C. Jiang, T.-H. Wu, and C.-H. Hsu*( 徐 駿森 ), “ Structural, Biophysical, and Biochemical Elucidation of the SARS-CoV-2 Nonstructural Protein 3 Macro Domain ”, ACS Infect. Dis. 6 , 2970 (2020). • Y.-C. Lou, C.-C. Chou, H.-H. Yeh, C.-Y. Chien, S. Sadotra, C.-H. Hsu*( 徐駿森 ), and C. Chen*( 陳金榜 ), “ Structural Basis for -35 Element Recognition by σ 4 Chimera Proteins and Their Interactions with PmrA Response Regulator ”, Proteins 88 , 69 (2020). • Y.-H. Peng, F.-Y. Liao, C.-T. Tseng, R. Kuppusamy, A.-S. Li, C.-H. Chen, Y.-S. Fan, S.-Y. Wang, M.-H. Wu, C.-C. Hsueh, J.-Y. Chang, L.-C. Lee, C. Shih, K.-S. Shia, T.- K. Yeh, M.-S. Hung, C.-C. Kuo, J.-S. Song, S.-Y. Wu*( 伍素瑩 ), and S.-H. Ueng* ( 翁紹華 ), “ Unique Sulfur-aromatic Interactions Contribute to the Binding of Potent Imidazothiazole Indoleamine 2,3-Dioxygenase Inhibitors ”, J. Med. Chem. 63 , 1642 (2020). • S. Sadotra, Y.-C. Lou, H.-C. Tang, Y.-C. Chiu, C.-H. Hsu*( 徐駿森 ), and C. Chen* ( 陳金榜 ), “ Structural Basis for Promoter DNA Recognition by the Response Regulator OmpR ”, J. Struct. Biol. 213 , 107638 (2020). • H. Sun, T.-P. Ko, W. Liu, W. Liu, Y. Zheng, C.-C. Chen*( 陳純琪 ), and R.-T. Guo* ( 郭瑞庭 ), “ Structure of an Antibiotic-synthesizing UDP-glucuronate 4-epimerase MoeE5 in Complex with Substrate ”, Biochem. Biophy. Res. Co. 521 , 31 (2020). List of Publications Publicaitons (including conference proceedings) listed here are based on the results obtained from facilities associated with NSRRC.