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NSRRC, users’ meeting, 2020, Taiwan Photon Source, industrial application, Soft X-ray Tomography
The NSRRC 2020 Annual Users’ Meeting & Workshops Was Held from November 10th to 12th
2021/01/07
Director Luo reported on NSRRC’s current status and future development at the users’ meeting. (For COVID-19 prevention purpose, attendees wore masks and kept a social distance during the meeting.)
The annual NSRRC Users' Meeting and Workshops convened November 10th to 12th, 2020. Co-hosted by the Chair of User Executive Committee (UEC), Prof. Tsan-Yao Chen (Natl. Tsing Hua Univ.) and the NSRRC scientist, Dr. Chen-Lin Liu, 472 people attended the meeting, including 75 invited speakers. Besides the annual users’ meeting, this year’s meeting featured three workshops, six interest group meetings, and a “NTUST-NSRRC Bilateral Meeting”.
 
The first day began with opening remarks from the UEC Chair, followed by an overview of NSRRC’s status and prospects by Director Gwo-Huei Luo. Prof. Pi-Tai Chou (Natl. Taiwan Univ.) delivered the keynote speech, titled “Fundamental and Applications of Materials via Control of Ground and Excited State Properties”. Later Dr. Ming-Chyuan Lin and Dr. Yu-Shan Huang updated the audience on recent progress within Light Source Division and Experimental Facility Division, respectively, before the Users’ Town Meeting was held.
 
From the afternoon of the first day to second day, 16 outstanding users gave invited talks on their latest research. The NSRRC Run on the second morning gathered 241 runners of users and NSRRC colleagues. The scientific program of the second day concluded with six breakout interest group meetings covering Protein X-ray Crystallography, Powder X-ray Diffraction, SR-based Microscopy, X-ray Absorption Spectroscopy, X-ray and Neutron Scattering, and Micro-Crystal X-ray Diffraction.
 
This year the Users’ Meeting lasted for three days so as to highlight more research results from the user community. Two poster sessions covered 238 presentations, including 65 registering as candidates for best popularity awards and 12 entering the final competition of oral presentations. The winners (see the table below) were given awards during the banquet. Prof. Hui-Chun Cheng (Natl. Tsing Hua Univ.) succeeded Prof. Chen as the UEC chair at the banquet which was held in the second evening.
 
 Poster Award Category Winner Advisor Affiliation
Oral Presentation:
Glory of Taiwan Award		 Biological Science Meng-Hsuan Lin Chun-Hua Hsu Natl. Taiwan Univ.
Materials Science Chen-Jui Huang Bing-Joe Hwang Natl. Taiwan Univ. of Sci. and Tech.
Physics/Chemistry Cheng-En Liu Chun-Fu Chang Natl. Chiao Tung Univ.
Oral Presentation:
Award of Recognition
(in alphabetical order)		 Biological Science Tzu-Lun Huang Kuo-Chiang Hsia Academia Sinica
You-Sheng Lin Kuen-Song Lin Yuan Ze Univ.
Roshan Babarao Satange Ming-Hon Hou Natl. Chung Hsing Univ.
Materials Science Soressa Abera Chala Bing-Joe Hwan Natl. Taiwan Univ. of Sci. and Tech.
Wei-En Ke Ying-Hao Chu Natl. Chiao Tung Univ.
Shih-Ho Lin Shan-Hui Hsu Natl. Taiwan Univ.
Physics/Chemistry Yen-Lin Cho Yu-Ting Liu Natl. Chung Hsing Univ.
Ashish Gandhi Sheng Yun Wu Natil. Dong Hwa Univ.
Poster:
Best Popularity Awards
(in alphabetical order)		 Biological Science Yu-Sung Huang Yuh-Ju Sun Natl. Tsing Hua Univ.
Wen-Hui Li Yu-Ting Liu Natl. Chung Hsing Univ.
Tung-Chang Liu Yu-Yuan Hsiao Natl. Chiao Tung Univ.
Thi Nhu Anh Than Yao-Tung Lin Natl. Chung Hsing Univ.
Materials Science Aswin Kumar Anbalagan Chih-Hao Lee Natl. Tsing Hua Univ.
Yin-Hsuan Chang Ming-Chung Wu Chang Gung Univ.
Kevin Chen Chia-Hao Chen/Yuan-Chieh Tseng Natl. Chiao Tung Univ.
Wei-Sheng Chiu Der-Hsin Wei NSRRC
Yu-Chang Lin Yan-Gu Lin Natl. Chiao Tung Univ.
Ndumiso Vukile Mdlovu Kuen-Song Lin Yuan Ze Univ.
Veeramani Rajendran Ru-Shi Liu Nat. Taipei Univ. of Tech.
Physics/Chemistry Aldrin Chang Chien-Cheng Kuo Natl. Sun Yat-sen Univ.
Wei-Hsiang Huang Wei-Nien Su Natl. Taiwan Univ. of Sci. and Tech.
Amol Singh Di-Jing Huang NSRRC
Wan-Zhen Xiao I-Jui Hsu Natl. Taipei Univ. of Tech.

Three topic-specific workshops were held on the third day. Summarized below are these workshops.
 
Workshop I: The Phase III Beamline Design and Construction of TPS
 
The beamline construction project of Taiwan Photon Source (TPS) was launched after the construction plan of the TPS. There are three phases of the beamline construction plan including 25 beamlines. Right after completion of the phase-II beamline construction, NSRRC will start the construction project of the 9 phase-III beamlines in January, 2021.
 
In this workshop, the phase-III beamlines were introduced to the attendees by NSRRC scientists, respectively. In the morning, the first session included TPS 11A In-Situ Serial Synchrotron Crystallography presented by Dr. Chun-Hsiang Huang and TPS 14A Small- and Wide- Angle X-ray Scattering Beamline presented by Dr. Chun-Jen Su. The second session consisted of TPS 20A Two Dimensional X-ray Diffraction Beamline by Dr. Yen-Chung Lai and TPS 47A High Energy Resolution X-ray Spectroscopy Beamline by Dr. Jin-Ming Chen.
 
In the afternoon, the third session included three presentations, which were TPS 38A X-ray Absorption Spectroscopy Beamline by Dr. Ting-Shan Chan, TPS 32A Tender X-ray Spectroscopy Beamline by Dr. Chi-Liang Chen, and TPS 33A Dragon Beamline at the TPS by Dr. Wen-Bin Wu. The final session consisted of TPS 43A Ambient/ Ultra-High Vacuum X-ray Photoelectron Spectroscopy by Dr. Chia-Hsin Wang and TPS 35A Concept Design and Construction for Soft X-ray Absorption Spectroscopy by Dr. Shu-Chih Haw.
 
In this informative workshop, the scientific goals and technical designs of the phase-III beamlines were presented and discussed. In total, 169 experts and students participated in the workshops and had a vibrant discussion with NSRRC scientists.
 
Workshop II: Synchrotron X-ray Techniques Facilitate Upgrade of Energy Industry
 
Renewable energy is an important topic not only for nowadays but also in the future. To develop advanced devices such as Li ion batteries, it is essential to understand the behavior of materials inside batteries under operation. Synchrotron X-ray is a good source providing required information. Consequently, the techniques have been used all over the world. In order to borrow experience from companies overseas to encourage companies in Taiwan to use synchrotron X-ray techniques, a workshop organized by NSRRC scientists Dr. Shi-Wei Chen and Dr. Chih-Wei Hu was thus hold on November 12th.
 
In the morning session, we invited Dr. Jim Lee (honorary chairman of Taiwan Battery Association) to give a keynote speech. Dr. Lee clearly introduced the policy and strategy of Li-ion batteries in Taiwan. Following, Dr. Shi-Wei Chen (NSRRC) clearly described synchrotron X-ray techniques that can be used for Li-ion batteries. Dr. Chih-Hung Shen (SYNergy ScienTech Corp.) noted the trend of material evolution for the battery used in wearable device. Dr. Hung-Ming Kang (E-ONE MOLI Energy Corp.) discussed key issues of Li-ion batteries that should be solved. Finally, Prof. Han-Yi Chen in Natl. Tsing Hua Univ. shared the experience how they used synchrotron X-ray to look into batteries.
 
The session in the afternoon started with the speaker of Dr. Kun-Sheng Shen in Gogoro Taiwan Limited. It was extremely interesting that Dr. Shen mentioned Gogoro Taiwan Limited using AI machine learning to control eight millions of batteries that circulated in the market. To predict failure of batteries in advanced is quite important for their work.Prof. Fu-Ming Wang in Natl. Taiwan Univ. of Sci. and Tech. thrown a clue about the essentiality of synchrotron X-ray to develop Li-ion battery with high energy density. Dr. Chung-Chieh Chang (CEO of GUS Technology) introduced required characteristics of cathodes in Li-ion battery. Dr. Po-Chin Chen in China Steel Chemical Corp. gave a talk about graphite anode they developed for the use in the next-generation Li-ion battery. Dr. Cheng-Zhang Lu in the Industrial Technology Research Institute talked about the analysis of cathode material by using advanced neutron diffraction. Finally, Prof. Tien-Chin Chang from Natl. Taipei Univ. of Tech. introduced recycle and reuse of Li-ion battery and the trend in the world.
 
This workshop provided a great opportunity for companies in Taiwan to understand synchrotron X-ray and audiences to grab key issues of the industry. The deep understanding about each other let corporation between NSRRC and industry become more and more possible. We expect synchrotron X-ray can help companies in Taiwan in many aspects, just like the situation in the world.
 
Workshop III: Applications of Soft X-ray Tomography in Biomedical Sciences
 
Soft X-ray tomography (SXT) is a newly developed technique to image three dimensional (3D) native cells in the biomedical applications. This workshop was organized by Dr. Lee-Jene Lai (NSRRC), and some domestic speakers were invited to present the motivation of applying SXT in the researches. The opening remark was delivered by Deputy Director of NSRRC Dr. Chun-Jung Chen to introduce the current development and future prospects of NSRRC in biomedical applications.
 
This workshop covered some topics of damaged organelles, nuclear structure, centriole and mitochondria. Dr. Fu-Tong Liu (Academia Sinica) shared his finding of granule-containing vesicles and morphological changes of mitochondrial in mast cell degranulation using SXT. He also found galectins accumulated around the damaged organelles, and would study the 3D morphological changes of damaged subcellular organelles and the localization of galectins around them by SXT. Two speakers discussed the nuclear structure. Prof. Shun-Fen Tzeng (Natl. Cheng Kung Univ.) reported the role of interleukin-33 (IL-33) mediated chromatin organization in Glial cell proliferation and differentiation, and would determine the structure of chromatin and chromosome in nuclear by SXT. Prof. Wei-hsuan Yu (Natl. Taiwan Univ.) introduced the gefitinib resistant lung cancer stem cell associated bulky-ball-like nucleolus as p53 molecular cage, and planned to reveal the detail architecture of the bulky-ball-like nucleolus by SXT. Dr. Tang K. Tang (Academia Sinica) described the deciphering the complex role of human microcephaly proteins in centriole duplication and ciliogenesis, and intended to image the centriole/centrosome duplication and cilia formation by SXT. Three speakers were studying the morphology of mitochondria. Prof. Chuang-Rung Chang (Natl. Tsing Hua Univ.) addressed clarifying mitochondrial network and organelle contacts in eukaryotic cells at metabolic. SXT image can provide the information of regulatory mechanisms of mitochondria dynamics to identify therapeutic targets in related diseases. Prof. Lu-Shiun Her (Natl. Cheng Kung Univ.) presented the roles of Huntingtin associated protein 40 (HAP40) in mitochondrial dysfunction of Huntington’s disease (HD) model cells and expected to understand the localization of a fraction of HAP40 in mitochondria by SXT. Dr. Chi-yu Fu (Academia Sinica) discussed the mitochondrial structure and network remodeling by cryo-electron tomography, and anticipated to study the fusion and fission processes of mitochondria in thick sample of whole cell by SXT. Dr. Lee-Jene Lai was the last speaker to introduce the scientific opportunities of soft X-ray tomography in bio-science. She also reported the current status and future prospects in TPS 24A.